Magnetic Resonance Imaging (MRI) Features in Diagnosing Tumefactive Demyelinating Lesion.

Background: A demyelinating lesion can present as a space occupying in Magnetic Resonance Imaging (MRI) brain. Lesions that have diameter greater than 2 cm is referred tumefactive lesion. These lesions mimic brain tumor, namely glioma or primary central nervous system lymphoma. Case presentation: We two female patients over 30 years old who presented with limb weakness. Their MRI demonstrated typical appearance of solitary, incomplete rim enhancing involved the subcortical white matter minimal mass effect. Also, enhancement opened to grey matter. Due their appearance, biopsy was not performed. The both reduced size upon follow up after treatment commencement and currently recovering. Conclusion: In this case report, we focus on discussing features its main differentials, which are lymphoma (CNSL) glioma.